Purpose: The purpose of this program is to utilize known topical medicants including hypochlorous acid (HOCL) versus normal saline (NS) for the nose/mouth to decrease the spread of pandemic respiratory viruses (PRV)including COVID-19.
Goal: Our goal is to implement a clinical program using hypochlorous acid to control the spread of COVID-19 by decrease the viral load in the upper airway and mouth.
Communities: COVID-19 pandemic is spreading world-wide in every continent. All people exposed to the virus are at risk for infection and some groups are at greater risk for serious infection and death. All over the world many peoples are more susceptible to PRV because of poverty, over crowed housing and the disabled or elderly ill in medical or long-term care facilities. These communities because social conditions are more likely to be infected and spread COVID-19 or others in their homes and communities.
Initial Implementation/Trials in the United States:
The outcome measure would include the number of new COVID-19 infections that occur within the MPH after 14 days. Tolerance to both medicants would be measured by self-report of any discomfort or other side effects. The study population would also include residents in long-term care facilities and the staff who care for them. Patients would be excluded for known chlorine sensitivity or allergy.
Second Trials Worldwide
A second trial would occur with the World Health Organizations' support in cooperating countries including India, Syria and Brazil in communities where the incidence of COVID-19 is unknown but at risk for the rapid spread of COVID-19 in these densely occupied housing. In these trials’ areas in MPH all family members would be started on HOCL sprays and confined to a limited geographic area. These restricted prophylactic treatment areas would be compared to other restricted areas who are receiving normal saline. Each week, for one month, these two areas would be assessed for presumptive cases of infection and COVID testing if available. Additionally, the staff managing this trial and other caseworkers in these test sites would be consented and randomly assigned HOCL versus NS.
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